Lonafarnib

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All Products are stable to be shipped at room temperature, unless otherwise specified.

Lonafarnib is an orally bioavailable tricyclic inhibitor of farnesyl protein transferase. It inhibits Rheb farnesylation and mTOR signaling and enhances taxane and tamoxifen antitumor activity. Studies show that it induces CCAAT/enhancer-binding protein homologous protein-dependent expression of death receptor 5, leading to induction of apoptosis in human cancer cells

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SKU RCL-TR-469445
CAS number 193275-84-2
Molecular Formula C27H31Br2ClN4O2
Catalog Number RCL-TR- 469445
Chemical Name Lonafarnib
Boiling Pt No Data Available
Molecular Weight 638.82
Melting Pt 150-152°C
Storage Condition Refrigerator
Stability No Data Available
Appearance White to Off-White Solid
Solubility Chloroform (Slightly), Methanol (Slightly)
HS Commidity Code 2933.39.4100