8-Epitacrolimus

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Synonyms :(-)-8-epi-Tacrolimus; [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8R*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]- 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,1

8-Epitacrolimus is a new l-pipecolic acid macrolide lactone, an important immunosuppressive drug that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. 8-Epitacrolimus is also an Epimer of Tacrolimus (F370000).

More Information
SKU RCLST038885
CAS number 129212-35-7
Molecular Formula C44H69NO12
Catalog Number RCLST038885
Chemical Name 8-Epitacrolimus
Synonyms (-)-8-epi-Tacrolimus; [3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8R*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]- 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-Hexadecahydro-5,19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,1
Molecular Weight 804.02
Solubility Chloroform (Slightly), Methanol (Slightly, Heated)
Stability No Data Available
Appearance Pale Yellow Solid
Storage Condition -20˚C Freezer, Under Inert Atmosphere
Shipping Info *eh* Dangerous Goods