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(S)-Hydroxy Des(boric Acid) Bortezomib

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All Products are stable to be shipped at room temperature, unless otherwise specified.
Synonyms :N-[(1S)-2-[[(1S)-1-hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-2-Pyrazinecarboxamide; N-[(1S)-2-[[(1S)-1-hydroxy-3-8methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-pyrazinecarboxamide; Bortezomib USP Impurity J

(S)-Hydroxy Des(boric Acid) Bortezomib is an impurity in the synthesis of Bortezomib (B675700), the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.

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SKU RCLST509539
CAS number 289472-81-7
Molecular Formula C19H24N4O3
Catalog Number RCLST509539
Chemical Name (S)-Hydroxy Des(boric Acid) Bortezomib
Synonyms N-[(1S)-2-[[(1S)-1-hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-2-Pyrazinecarboxamide; N-[(1S)-2-[[(1S)-1-hydroxy-3-8methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-pyrazinecarboxamide; Bortezomib USP Impurity J
Molecular Weight 356.42
Solubility Chloroform (Slightly), Methanol (Slightly)
Stability No Data Available
Appearance White to Off-White Solid
Storage Condition -20°C Freezer

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