3-Keto-N-aminoethyl-N’-aminocaproyldihydrocinnamoyl Cyclopamine

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All Products are stable to be shipped at room temperature, unless otherwise specified.
Synonyms :KAAD-Cyclopamine;

Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects of oncogenic mutations in Smoothened and Patched.1 The KAAD-Cyclopamine has shown 10-20 fold higher potency than cyclopamine in inhibition of ß-Galactosidase expression in p2Ptch-1- cells, with similar or lower toxicity. KAAD-Cyclopamine compound is unstable in solution.

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SKU RCLST000171
CAS number 306387-90-6
Molecular Formula C44H63N3O4
Catalog Number RCLST000171
Chemical Name 3-Keto-N-aminoethyl-N’-aminocaproyldihydrocinnamoyl Cyclopamine
Synonyms KAAD-Cyclopamine;
Boiling Pt No Data Available
Molecular Weight 697.99
Melting Pt >90°C (dec.)
Storage Condition Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Stability No Data Available
Appearance Off-White to Yellow Solid
Solubility Chloroform (Slightly), Methanol (Slightly)
HS Commidity Code 2933.99.9701