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Andrographolide
In stock
Andrographolide is a labdane diterpenoid (2). Andrographolide is the main bioactive component isolated from the medicinal plant Andrographis paniculata (2). Andrographolide showed significant antihepatotoxic action in P. berghei K173-induced hepatic damage in M. natalensis(1). Andrographolide inhibits tumor necrosis factor-α (TNF-α)-induced intercellular adhesion mol.-1 (ICAM-1) expression and adhesion of HL-60 cells onto human umbilical vein endothelial cells (HUVEC), which are associated with inflammatory diseases (2). These findings suggest that Andrographolide may have potential as a cardiovascular-protective agent.
| SKU | RCLST574736 |
|---|---|
| CAS number | 5508-58-7 |
| Molecular Formula | C20H30O5 |
| Catalog Number | RCLST574736 |
| Chemical Name | Andrographolide |
| Synonyms | (3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone; [1R-[1α[E(S*)],4aβ,5α,6α,8aα]]-3-[2-[Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-meth |
| Molecular Weight | 350.45 |
| Solubility | Acetic Acid (Slightly), DMSO (Slightly), Methanol (Slightly) |
| Stability | No Data Available |
| Appearance | White Solid |
| Storage Condition | Refrigerator |