Entrectinib
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SKU | RCLST303955 |
---|---|
CAS number | 1108743-60-7 |
Molecular Formula | C₃₁H₃₄F₂N₆O₂ |
Catalog Number | RCLST303955 |
Chemical Name | Entrectinib |
Synonyms | N-[5-[(3,5-Difluorophenyl)methyl]-1H-indazol-3-yl]-4-(4-methyl-1-piperazinyl)-2-[(tetrahydro-2H-pyran-4-yl)amino]benzamide; RXDX 101 |
Molecular Weight | 560.64 |
Application Note | Entrectinib, also known as RXDX-101 and NMS-E628, is an oral small molecule inhibitor of TrkA, TrkB and TrkC, as well as ROS1 and ALK, with high potency and selectivity. RXDX-101 has demonstrated potent pharmacological activity in preclinical studies and |
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