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Geldanamycin

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All Products are stable to be shipped at room temperature, unless otherwise specified.
Synonyms :9,13-Dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione 9-Carbamate; (+)-Geldanamycin; NSC 122750; NSC 212518;

Geldanamycin is a potent antitumor antibiotic active at nanomolar concentration against 60 cell lines. It binds specifically to the heat shock protein Hsp90 and to its endoplasmic reticulum homologue GP96, and thus interferes with conformational maturation of proteins and the cellular stress response. In addition, it is a potent inhibitor of the nuclear hormone receptor family.

More Information
SKU RCLST005403
CAS number 30562-34-6
Molecular Formula C29H40N2O9
Catalog Number RCLST005403
Chemical Name Geldanamycin
Synonyms 9,13-Dihydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-2-azabicyclo[16.3.1]docosa-4,6,10,18,21-pentaene-3,20,22-trione 9-Carbamate; (+)-Geldanamycin; NSC 122750; NSC 212518;
Molecular Weight 560.64
Solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability No Data Available
Appearance Yellow to Orange Solid
Storage Condition -20°C Freezer

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Geldanamycin