Isoliquiritigenin

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Synonyms :(2E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one; ISL; 2',4,4'-Trihydroxychalcone; 2',4,4'-Trihydroxychalcone; GU 17;

Isoliquiritigenin (ISL) is a flavonoid found in licorice root and several other plants that displays antioxidant, anti-inflammatory, and antitumor activities as well as hepatoprotection against steatosis-induced oxidative stress. ISL induces quinone reductase-1, a phase II enzyme that deactivates radicals and electrophiles, with a concentration required to double activity (CD) value of 1.8 μM in murine hepatoma cells.

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SKU RCLST058028
CAS number 961-29-5
Molecular Formula C15H12O4
Catalog Number RCLST058028
Chemical Name Isoliquiritigenin
Synonyms (2E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one; ISL; 2',4,4'-Trihydroxychalcone; 2',4,4'-Trihydroxychalcone; GU 17;
Molecular Weight 256.25
Solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability No Data Available
Appearance Yellow Solid
Storage Condition Refrigerator
Isoliquiritigenin