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Necrostatin-1

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All Products are stable to be shipped at room temperature, unless otherwise specified.
Synonyms :5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone; 5-(Indol-3-ylmethyl)-3-methyl-2-thiohydantoin; Nec 1;

Necroptosis is a regulated caspase-independent cell death mechanism that results in morphological features resembling necrosis. Necrostatin-1 is an inhibitor of RIP1 kinase that prevents the death of TNF-α-treated FADD-deficient Jurkat cells. Necrostatin-1 has been used to investigate the pathological importance of necroptosis in ischemic brain injury and myocardial infarction.

More Information
SKU RCLST055883
CAS number 4311-88-0
Molecular Formula C13H13N3OS
Catalog Number RCLST055883
Chemical Name Necrostatin-1
Synonyms 5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone; 5-(Indol-3-ylmethyl)-3-methyl-2-thiohydantoin; Nec 1;
Molecular Weight 259.33
Solubility DMSO (Slightly), Methanol (Slightly)
Stability No Data Available
Appearance Yellow Solid
Storage Condition Refrigerator

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