Necrostatin-1

Availability:In stock

Quantity:

Note:

All Products are stable to be shipped at room temperature, unless otherwise specified.

Synonyms :5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone; 5-(Indol-3-ylmethyl)-3-methyl-2-thiohydantoin; Nec 1;

Description

Necroptosis is a regulated caspase-independent cell death mechanism that results in morphological features resembling necrosis. Necrostatin-1 is an inhibitor of RIP1 kinase that prevents the death of TNF-α-treated FADD-deficient Jurkat cells. Necrostatin-1 has been used to investigate the pathological importance of necroptosis in ischemic brain injury and myocardial infarction.

More Information

More Information
SKU	RCLST055883
CAS number	4311-88-0
Molecular Formula	C13H13N3OS
Catalog Number	RCLST055883
Chemical Name	Necrostatin-1
Synonyms	5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone; 5-(Indol-3-ylmethyl)-3-methyl-2-thiohydantoin; Nec 1;
Molecular Weight	259.33
Solubility	DMSO (Slightly), Methanol (Slightly)
Stability	No Data Available
Appearance	Yellow Solid
Storage Condition	Refrigerator

Necrostatin-1

Categories