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PF-4708671

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Synonyms :2-[[4-(5-ethyl-4-pyrimidinyl)-1-piperazinyl]methyl]-6-(trifluoromethyl)-1H-benzimidazole; PF 4708671;

Description

PF-4708671 is a highly specific inhibitor of p70 ribosomal S6 kinase (S6K1). PF-4708671 inhibits S6K1-mediated phosphorylation of S6 protein in response to IGF-1 (insulin-like growth factor 1), while having no effect on highly related RSK (p90 ribosomal S6 kinase) and MSK (mitogen- and stress-activated kinase) kinases.

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More Information
SKU	RCLST010492
CAS number	1255517-76-0
Molecular Formula	C19H21F3N6
Catalog Number	RCLST010492
Chemical Name	PF-4708671
Synonyms	2-[[4-(5-ethyl-4-pyrimidinyl)-1-piperazinyl]methyl]-6-(trifluoromethyl)-1H-benzimidazole; PF 4708671;
Molecular Weight	390.41
Solubility	DMSO (Slightly, Sonicated), Methanol (Slightly)
Stability	No Data Available
Appearance	Pale Purple Solid
Storage Condition	-20˚C Freezer

PF-4708671

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