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Pitavastatin-d5 Lactone

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All Products are stable to be shipped at room temperature, unless otherwise specified.
Synonyms :(4R,6S)-6-[(1E)-2-[2-(Cyclopropyl-d5)-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-one; [4R-[4α,6β(E)]]-6-[2-[2-(Cyclopropyl-d5)-4- (4-fluorophenyl)-3-quinolinyl]ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-one; NK 104-d5; NK 104-d5

A labelled metabolite of Pitavastatin. Recent studies have shown that conversion between acid and lactone forms occurs in the body, drug-drug interaction should be considered on both acid and lactone forms. The inhibitory effects of statins on CYP metabolic activities and MDR1 transporting activity were investigated using human liver microsomes and MDR1-overexpressing LLC-GA5-COL150 cells.

More Information
SKU RCLST220135
Molecular Formula C25H17D5FNO3
Catalog Number RCLST220135
Chemical Name Pitavastatin-d5 Lactone
Synonyms (4R,6S)-6-[(1E)-2-[2-(Cyclopropyl-d5)-4-(4-fluorophenyl)-3-quinolinyl]ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-one; [4R-[4α,6β(E)]]-6-[2-[2-(Cyclopropyl-d5)-4- (4-fluorophenyl)-3-quinolinyl]ethenyl]tetrahydro-4-hydroxy-2H-pyran-2-one; NK 104-d5; NK 104-d5
Molecular Weight 408.48
Solubility Chloroform (Slightly), Ethyl Acetate (Slightly)
Stability No Data Available
Appearance White to Pale Yellow Solid
Storage Condition Hygroscopic, -20˚C Freezer, Under Inert Atmosphere

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Pitavastatin-d5 Lactone