Semagacestat

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Synonyms :(2S)-2-Hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]butanamide; LY 450139;

Description

Semagacestat is an inhibitor of the γ-secretase enzyme. γ-Secretase enzyme is pivotal in the generation of β-amyloid (Aβ), a neurotoxic endogenous peptide believed to be involved in the pathogenesis of Alzheimer's disease (AD).

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More Information
SKU	RCLST006552
CAS number	425386-60-3
Molecular Formula	C19H27N3O4
Catalog Number	RCLST006552
Chemical Name	Semagacestat
Synonyms	(2S)-2-Hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]butanamide; LY 450139;
Molecular Weight	361.44
Solubility	DMSO (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
Stability	No Data Available
Appearance	White Solid
Storage Condition	-20˚C Freezer

Semagacestat

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