Semagacestat is an inhibitor of the γ-secretase enzyme. γ-Secretase enzyme is pivotal in the generation of β-amyloid (Aβ), a neurotoxic endogenous peptide believed to be involved in the pathogenesis of Alzheimer's disease (AD).
SKU | RCLST006552 |
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CAS number | 425386-60-3 |
Molecular Formula | C19H27N3O4 |
Catalog Number | RCLST006552 |
Chemical Name | Semagacestat |
Synonyms | (2S)-2-Hydroxy-3-methyl-N-[(1S)-1-methyl-2-oxo-2-[[(1S)-2,3,4,5-tetrahydro-3-methyl-2-oxo-1H-3-benzazepin-1-yl]amino]ethyl]butanamide; LY 450139; |
Molecular Weight | 361.44 |
Solubility | DMSO (Slightly), Dichloromethane (Slightly), Methanol (Slightly) |
Stability | No Data Available |
Appearance | White Solid |
Storage Condition | -20˚C Freezer |