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- TPCA-1
TPCA-1 is a direct dual inhibitor for both IKKβ (IKK-2) and STAT3. It inhibits STAT3 phosphorylation, DNA binding, and transactivation in vivo. Synergistic treatment of TPCA-1 with tyrosine kinase inhibitors (TKIs) can potentially be a more effective method for treating cancers.
| SKU | RCLST005007 |
|---|---|
| CAS number | 507475-17-4 |
| Molecular Formula | C12H10FN3O2S |
| Catalog Number | RCLST005007 |
| Chemical Name | TPCA-1 |
| Molecular Weight | 279.29 |
| Solubility | DMSO (Slightly), Methanol (Slightly) |
| Stability | No Data Available |
| Appearance | Pale Beige Solid |
| Storage Condition | -20°C Freezer |
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