Withaferin A is a promising anticancer constituent of Ayurvedic medicinal plant Withania somnifera. Withaferin A showed potent cytotoxicity against human head and neck squamous cell carcinoma (JMAR and MDA-1986). Withaferin A has recently been found to be a leptin sensitizer that can reduce the weight in obese mice fed in a high-fat diet (see C249500).
SKU | RCLST002994 |
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CAS number | 5119-48-2 |
Molecular Formula | C28H38O6 |
Catalog Number | RCLST002994 |
Chemical Name | Withaferin A |
Synonyms | (4β,5β,6β,22R)-5,6-Epoxy-4,22,27-trihydroxy-1-oxoergosta-2,24-dien-26-oic Acid δ-Lactone; (20S,22R)-5,6β-Epoxy-4β,22,27-trihydroxy-1-oxo-5β-ergosta- 2,24-dien-26-oic Acid δ-Lactone; NSC 101088; NSC 273757; Withaferine; Withaferine A; |
Molecular Weight | 470.6 |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Stability | No Data Available |
Appearance | White to Off-White Solid |
Storage Condition | -20˚C Freezer |