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A tankyrase (TNKS) inhibitor that antagonizes Wnt signaling via stimulation of β-catenin degradation and stabilization of axin. XAV 939 inhibits proliferation of the μ-catenin-dependent colon carcinoma cell line DLD-1.
| SKU | RCLST000447 |
|---|---|
| CAS number | 284028-89-3 |
| Molecular Formula | C14H11F3N2OS |
| Catalog Number | RCLST000447 |
| Chemical Name | XAV 939 |
| Synonyms | 1,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one; NVP-XAV 939; |
| Molecular Weight | 312.31 |
| Solubility | DMSO (Slightly), Methanol (Very Slightly) |
| Stability | No Data Available |
| Appearance | White to Pale Yellow Solid |
| Storage Condition | -20°C Freezer |
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