Cytomegalovirus DNA (Towne∆147 BAC) for DNA Measurements

This Standard Reference Material (SRM) is intended for use in the value assignment of the number of amplifiable genome copies of cytomegalovirus (CMV) per volume sample.

When used to value assign practical CMV calibration materials, SRM 2366a can provide traceability to the International System of Units (SI) for measurement results of CMV viral load in tissues or fluids such as plasma.

A unit of SRM 2366a consists of one sterile, 0.5 mL perfluoroalkoxy (PFA) fluoropolymer vial containing approximately 150 μL of extracted DNA solubilized in TE buffer, pH 8.0. TE buffer consists of 10 mmol/L 2 amino 2 (hydroxymethyl)-1,3-propanediol (Tris) and 1mmol/L ethylenediaminetetraacetic acid (EDTA) tetrasodium salt in deionized water.

The CMV DNA is in the form of a bacterial artificial chromosome – known as CMV TowneΔ147 BAC – that contains the genome of the Towne strain of CMV .

Manufacturer: NIST ( National Institute of Standards and Technology)