3-Methyl-3-(phenylmethoxy)butanamide is an intermediate used in the synthesis of (S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2yl]pyrazine-2-carboxamide (H805105), which is an impurity of bortezomib (B675700), which is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus and cytosol of all eukaryotic cells. Targets the ubiquitin-proteasome pathway.
SKU | RCLST853622 |
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CAS number | 121490-17-3 |
Molecular Formula | C12H17NO2 |
Catalog Number | RCLST853622 |
Chemical Name | 3-Methyl-3-(phenylmethoxy)butanamide |
Boiling Pt | No Data Available |
Molecular Weight | 207.27 |
Melting Pt | No Data Available |
Storage Condition | -20°C Freezer |
Stability | No Data Available |
Appearance | Pale Yellow Liquid |
Solubility | Dichloromethane; Methanol |